EVERYDAY SCIENCE

Detailed explanation-1: -Clotting factors: Clotting factors and von Willebrand factor (vWF) found in plasma play an essential role in blood clotting and are activated by damage to the endothelium resulting in exposure of collagen found beneath the endothelium of the blood vessel.

Detailed explanation-2: -When a blood vessel becomes injured, the coagulation factors or clotting factors in the blood are activated. The clotting factor proteins stimulate the production of fibrin, which is a strong and strand-like substance that forms a fibrin clot.

Detailed explanation-3: -Blood clotting factors Thrombin converts fibrinogen, a blood clotting factor that is normally dissolved in blood, into long strands of fibrin that radiate from the clumped platelets and form a net that entraps more platelets and blood cells.

Detailed explanation-4: -Fibrinogen… A specialized protein or clotting factor found in blood. When a blood vessel is injured, thrombin, another clotting factor, is activated and changes fibrinogen to fibrin.