EVERYDAY SCIENCE

Detailed explanation-1: -Symptoms of acromegaly include an enlarged face and hands. Changes to the face may cause the brow bone and lower jawbone to protrude, and the nose and lips to get larger. Acromegaly is a hormonal disorder that develops when your pituitary gland produces too much growth hormone during adulthood.

Detailed explanation-2: -Gigantism, also called pediatric acromegaly and pituitary gigantism, is a very rare condition that happens when a child or adolescent has high levels of growth hormone (GH) in their body, which causes them to grow very tall.

Detailed explanation-3: -A lack of growth hormone is usually caused by damage to the pituitary gland or the hypothalamus, a part of the brain that controls the pituitary gland. The damage may be due to a tumor; to surgery or radiation used to treat the tumor; or to problems with the blood supply to the pituitary gland.

Detailed explanation-4: -Growth hormone deficiency (GHD), also known as dwarfism or pituitary dwarfism, is a condition caused by insufficient amounts of growth hormone in the body. Children with GHD have abnormally short stature with normal body proportions.

Detailed explanation-5: -Gigantism occurs when growth hormone hypersecretion occurs before the fusion of the long bone epiphysis and is characterized by tall stature. Acromegaly occurs when GH hypersecretion occurs after the fusion of the epiphysis leading to large extremities and characteristic facies.