EVERYDAY SCIENCE

Detailed explanation-1: -Autoimmune diabetes mellitus or T1DM is an organ-specific autoimmune disease that affects the insulin-producing pancreatic beta cells, after an inflammatory process leads to a chronic deficiency of insulin in genetically susceptible individuals (1).

Detailed explanation-2: -We know type 1a diabetes is caused by an autoimmune process in the body that mistakenly destroys the insulin-producing cells, or beta cells and occurs in genetically predisposed individuals. What starts the autoimmune destruction is unknown, but it may be due to environmental factors.

Detailed explanation-3: -Type 1 diabetes is thought to be caused by an autoimmune reaction (the body attacks itself by mistake). This reaction destroys the cells in the pancreas that make insulin, called beta cells. This process can go on for months or years before any symptoms appear.

Detailed explanation-4: -In most people with type 1 diabetes, the body’s immune system, which normally fights infection, attacks and destroys the cells in the pancreas that make insulin. As a result, your pancreas stops making insulin.

Detailed explanation-5: -Insulin resistance happens when your body requires a high amount of insulin to manage blood glucose (also known as blood sugar). Insulin resistance is a problem found in people with prediabetes and type 2 diabetes, but it people with type 1 diabetes can become insulin resistant, too.