EVERYDAY SCIENCE

SCIENCE

ENDOCRINE GLANDS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Hypersecretion of cortisol, often due to adrenal tumor, can lead to “moon face” feature and “buffalo hump". Elevated blood sugar is another sign.
A
Goiter
B
Grave’s Disease
C
Cushing Syndrome
D
Addison’s Disease
Explanation: 

Detailed explanation-1: -Too much cortisol can cause some of the hallmark signs of Cushing syndrome-a fatty hump between your shoulders, a rounded face, and pink or purple stretch marks on your skin. Cushing syndrome can also result in high blood pressure, bone loss and, on occasion, type 2 diabetes.

Detailed explanation-2: -Cushing’s syndrome (also called Cushing syndrome) is the name given to hypersecretion of cortisol (or hypercortisolism). Cushing’s syndrome causes a very characteristic type of central obesity. There is weight gain in the trunk and face, but a loss of muscle mass and adipose tissue in the arms and legs.

Detailed explanation-3: -Cushing’s disease is caused by endogenous hypercortisolism. This is due to the hypersecretion of the adrenocorticotropic hormone (ACTH) by an ACTH-secreting pituitary adenoma [1]. It is considered a rare condition, though it is recognized as a cause of Cushing’s syndrome [2].

Detailed explanation-4: -The most common cause of Cushing’s syndrome is the long-term, high-dose use of the cortisol-like glucocorticoids. These medicines are used to treat other medical conditions, such as asthma link, rheumatoid arthritis link, and lupus link.

Detailed explanation-5: -Moon facies occurs when extra fat builds up on the sides of the face. It is often related to obesity but can be from Cushing’s syndrome. That’s why people sometimes refer to it as a Cushingoid appearance. Cushing’s syndrome occurs when the body is exposed for long periods to high levels of a hormone called cortisol.

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