EVERYDAY SCIENCE

Detailed explanation-1: -the mineralocorticoid receptor (MR) is essential for blood pressure regulation and electrolyte homeostasis. Physiologically, the MR mediates effects of the hormone aldosterone on electrolyte balance, promoting Na+ retention and K+ excretion.

Detailed explanation-2: -The major effect of mineralocorticoids is the regulation of electrolyte excretion in the kidney. Aldosterone treatment results in increased sodium reabsorption and an increase in excretion of potassium and hydrogen in the renal tubule.

Detailed explanation-3: -Mineralocorticoids, such as aldosterone, promote sodium reabsorption in transporting epithelia of the kidneys, salivary glands, and large intestine. Sodium reabsorption is followed by passive reabsorption of water.

Detailed explanation-4: -Aldosterone (ALD) is a hormone your adrenal glands release that helps regulate blood pressure by managing the levels of sodium and potassium in your blood. Sodium and potassium are electrolytes.

Detailed explanation-5: -The mineralocorticoid receptor (MR) and mineralocorticoids regulate epithelial handling of electrolytes, and induces diverse effects on other tissues. Traditionally, the effects of MR were ascribed to ligand-receptor binding and activation of gene transcription.