EVERYDAY SCIENCE

Detailed explanation-1: -one gene–one enzyme hypothesis, idea advanced in the early 1940s that each gene controls the synthesis or activity of a single enzyme. The concept, which united the fields of genetics and biochemistry, was proposed by American geneticist George Wells Beadle and American biochemist Edward L.

Detailed explanation-2: -A mutation can alter a gene so it no longer produces the normal enzyme, resulting in a physical symptom, like the need for nutritional supplements. Beadle and Tatum proposed that, in general, each gene directs the formation of one (and only one) enzyme.

Detailed explanation-3: -The one gene–one enzyme hypothesis, proposed by George Wells Beadle in the US in 1941, is the theory that each gene directly produces a single enzyme, which consequently affects an individual step in a metabolic pathway.

Detailed explanation-4: -Which statement is most consistent with the one gene, one enzyme hypothesis originally proposed by Beadle and Tatum? Every enzyme makes one gene.

Detailed explanation-5: -Beadle and Tatum proposed the “one gene one enzyme” theory. One gene codes for the production of one protein. “One gene one enzyme” has since been modified to “one gene one polypeptide” since many proteins (such as hemoglobin) are made of more than one polypeptide.