EVERYDAY SCIENCE

Detailed explanation-1: -Depending on the location, different glial cell types make myelin in a different manner. Schwann cells make myelin in the peripheral nervous system (PNS: nerves) and oligodendrocytes in the central nervous system (CNS: brain and spinal cord). In the PNS, one Schwann cell forms a single myelin sheath (Figure 1A).

Detailed explanation-2: -CNS myelin is produced by special cells called oligodendrocytes. PNS myelin is produced by Schwann cells. The two types of myelin are chemically different, but they both perform the same function-to promote efficient transmission of a nerve impulse along the axon.

Detailed explanation-3: -Schwann cells (SCs) are a type of glial cell that surrounds neurons, keeping them alive and sometimes covering them with a myelin sheath, and are the major glial cell type in the peripheral nervous system. They play essential roles in the development, maintenance, function, and regeneration of peripheral nerves.

Detailed explanation-4: -The Schwann cell plays a vital role in maintaining the peripheral nervous system (PNS). Schwann cells are derived from neural crest cells, and come in two types either myelinating or non-myelinating Schwann cells. Both play a pivotal role in the maintenance and regeneration of axons of the neurons in the PNS.