EVERYDAY SCIENCE

Detailed explanation-1: -The proteins in enzymes are usually globular. The intra-and intermolecular bonds that hold proteins in their secondary and tertiary structures are disrupted by changes in temperature and pH. This affects shapes and so the catalytic activity of an enzyme is pH and temperature sensitive.

Detailed explanation-2: -Enzymes are also sensitive to temperature. Many work best at temperatures close to body temperatures and most lose their ability to catalyse if they are heated above 60 or 70 degrees Celcius. Graph of enzyme-catalysed reaction rate against temperature.

Detailed explanation-3: -Enzymes are biological catalysts. Just like other catalysts, they reduce activation energy, allowing reactions to proceed in a desired direction. Because their activity is dependent on the folding of a protein, they are usually sensitive to the temperature, pH, and salt concentration of the environment they work in.

Detailed explanation-4: -The range of pH in which the enzyme mixture shows high activity is strongly temperature dependent.

Detailed explanation-5: -Higher temperature generally causes more collisions among the molecules and therefore increases the rate of a reaction. More collisions increase the likelihood that substrate will collide with the active site of the enzyme, thus increasing the rate of an enzyme-catalyzed reaction.