EVERYDAY SCIENCE

Detailed explanation-1: -Bones grow in length at the epiphyseal plate by a process that is similar to endochondral ossification. The cartilage in the region of the epiphyseal plate next to the epiphysis continues to grow by mitosis.

Detailed explanation-2: -The epiphyseal plate is the area of growth in a long bone. It is a layer of hyaline cartilage where ossification occurs in immature bones. On the epiphyseal side of the epiphyseal plate, cartilage is formed. On the diaphyseal side, cartilage is ossified, allowing the diaphysis to grow in length.

Detailed explanation-3: -The epiphyseal growth plate is the main site of longitudinal growth of the long bones. At this site, cartilage is formed by the proliferation and hypertrophy of cells and synthesis of the typical extracellular matrix. The formed cartilage is then calcified, degraded, and replaced by osseous tissue.

Detailed explanation-4: -Growth plates, also called physes or epiphyseal plates, are discs of cartilage present in growing children. They are located between the middle and the end of the long bones, such as the bones of the arms and legs. Most long bones have one growth plate at each end.