EVERYDAY SCIENCE

Detailed explanation-1: -The cell responsible for bone resorption, or breakdown, is the osteoclast, which is found on bone surfaces, is multinucleated, and originates from monocytes and macrophages (two types of white blood cells) rather than from osteogenic cells.

Detailed explanation-2: -Osteoprogenitor cells residing in the bone marrow give rise to osteoblasts that progress through a series of maturational stages resulting in the mature osteocyte.

Detailed explanation-3: -Stem cells of bone, also called osteogenic cells or osteoprogenitor cells, are undifferentiated cells having a high mitotic activity. These precursors found in bone marrow differentiate to form bone-forming osteoblasts, mainly incorporating calcium in the bone matrix.

Detailed explanation-4: -4.2. Osteoblasts are the bone cells derived from osteochondral progenitor cells that form the bone through a process called ossification. Osteoblasts result in the formation of new layers of bone by producing a matrix that covers the older bone surface.

Detailed explanation-5: -Committed osteoprogenitor cells then proliferate, differentiate into postmitotic osteoblasts that synthesize and mineralize bone matrix, and finally become terminally differentiated osteocytes or quiescent bone lining cells.