EVERYDAY SCIENCE

Detailed explanation-1: -In most cases, getting chickenpox once means you will not get it again. This is called lifelong immunity.

Detailed explanation-2: -Recovery from primary varicella infection usually provides immunity for life. In otherwise healthy people, a second occurrence of varicella is uncommon. Second occurrence of varicella may be more likely to occur in people who are immunocompromised.

Detailed explanation-3: -Varicella-zoster virus is sensed by the innate immune system via pattern recognition receptors that recognize viral pathogen-associated molecular patterns.

Detailed explanation-4: -Chickenpox infection demonstrates how effective the adaptive immune response can be in preventing reinfection with the chickenpox virus.

Detailed explanation-5: -Chickenpox is transmitted from person to person by directly touching the blisters, saliva or mucus of an infected person. The virus can also be transmitted through the air by coughing and sneezing.