EVERYDAY SCIENCE

Detailed explanation-1: -Lymph nodes contain lymphocytes, a type of white blood cell, and are primarily made up of B cells and T cells. B cells are mainly found in the outer cortex where they are clustered together as follicular B cells in lymphoid follicles, and T cells and dendritic cells are mainly found in the paracortex.

Detailed explanation-2: -Anatomy of a lymph node. The T and B cells enter through the high endothelial venules while phagocytes bring antigen through afferent lymphatic vessels. Germinal centers are areas in the cortex where B cell activation and somatic hypermutation occur.

Detailed explanation-3: -Lymph nodes have 2 distinct regions, the cortex and the medulla. The cortex contains follicles, which are collections of lymphocytes. At the center of the follicles is an area called germinal centers that predominantly host B-lymphocytes while the remaining cells of the cortex are T-lymphocytes.

Detailed explanation-4: -Lymph nodes filter substances that travel through the lymphatic fluid, and they contain lymphocytes (white blood cells) that help the body fight infection and disease. There are hundreds of lymph nodes found throughout the body. They are connected to one another by lymph vessels.