GROSS ANATOMY

Detailed explanation-1: -The sympathetic nervous system normally controls facial sweating. However, after injury to postganglionic sympathetic fibres, parasympathetic fibres sometimes make functional connections with sweat glands, so that parasympathetic reflexes provoke pathological sweating.

Detailed explanation-2: -The underlying cause of hyperhidrosis is over activity of the sympathetic nervous system. The sympathetic nervous system activates our fight or flight response, which includes increased heart rate, increased blood pressure, and sweating.

Detailed explanation-3: -The sweat glands are innervated by the sympathetic nervous system and are part of the fight or flight response system. Their innervation consists of two parts, a preganglionic and postganglionic neuron.

Detailed explanation-4: -sweat glands are innervated by both cholinergic and adrenergic neurons (49) and respond to both cholinergic (5, 40, 43) and adrenergic (10, 43, 44) agonists. Contribution of the cholinergic mechanism to sweating during exercise is well recognized (44–46).