GROSS ANATOMY

Detailed explanation-1: -Mixed nerves contain both types of fibers. A connective tissue sheath called the epineurium surrounds each nerve. Each bundle of nerve fibers is called a fasciculus and is surrounded by a layer of connective tissue called the perineurium.

Detailed explanation-2: -PERINEURIUM. Each fascicle is surrounded by a connective tissue sheath, the perineurium. The perineurium consists of concentric layers of flattened cells separated by layers of collagen (Figures 12 to 16). The number of perineurial cell layers depends on the size of the fascicle.

Detailed explanation-3: -A nerve is formed by a collection of nerve fascicles (bundle of nerve fibers) which are surrounded by a loose connective tissue sheath known as the epineurium. The epineurium is the outermost layer of a peripheral nerve and is the strongest of all the connective tissue layers of the nerve.

Detailed explanation-4: -Anatomy of the Peripheral Nerve Deep to the epineurium, the internal epineurium provides a loose connective tissue for the individual fascicular bundles surrounded by the perineurium.

Detailed explanation-5: -The nerve trunk is made up of fascicles composed of endoneurial units, each of which is surrounded by an endoneurium composed of a basement membrane and a thin connective tissue sheath. Each fascicle is invested with a perineurial connective tissue sheath, and an epineurium surrounds the fascicles.