GROSS ANATOMY

Detailed explanation-1: -Theendoneurium is a thin layer of collagenous connective tissue that surrounds individual nerve fibers and is continuous with the fine layer of connective tissue of the nerve roots. In the nerve trunk, bundles of myelinated and unmyelinated nerve fibers are arranged intofascicles (or funiculi).

Detailed explanation-2: -Each bundle of nerve fibers is called a fasciculus and is surrounded by a layer of connective tissue called the perineurium. Within the fasciculus, each individual nerve fiber, with its myelin and neurilemma, is surrounded by connective tissue called the endoneurium.

Detailed explanation-3: -In the PNS, each nerve fiber is surrounded by a layer of connective tissue called the endoneurium. In most nerves, longitudinal axon bundles form fascicles, each wrapped in another sleeve, composed of layers of overlapping cells called the perineurium.

Detailed explanation-4: -The endoneurium also called intrafascicular connective tissue or Henle’s sheath is a connective tissue sheath that directly surrounds individual Schwann cell–axon units (myelinated axon surrounded by Schwann cells) of peripheral nerves and accompanying endoneurial capillaries that supply the nerve axons.

Detailed explanation-5: -A nerve is formed by a collection of nerve fascicles (bundle of nerve fibers) which are surrounded by a loose connective tissue sheath known as the epineurium. The epineurium is the outermost layer of a peripheral nerve and is the strongest of all the connective tissue layers of the nerve.