LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

APPLIED BIOTECHNOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What kind of mutation is a missense mutation?
A
when a nitrogen base is substituted and the wrong amino acid is added (the protein made may or may not function)
B
when a nitrogen base is substituted and a stop is added causing no protein to be made
C
when a gene is added and twice the protein is made
D
when a gene is deleted and no protein is made
Explanation: 

Detailed explanation-1: -A missense mutation can be a point mutation. A point mutation is where you change one base in the DNA to another. A missense mutation occurs when that point mutation causes a different amino acid to be placed from that codon.

Detailed explanation-2: -A genetic alteration in which a single base pair substitution alters the genetic code in a way that produces an amino acid that is different from the usual amino acid at that position. Some missense variants (or mutations) will alter the function of the protein. Also called missense variant.

Detailed explanation-3: -Substitution Substitution, as related to genomics, is a type of mutation in which one nucleotide is replaced by a different nucleotide. The term can also refer to the replacement of one amino acid in a protein with a different amino acid.

Detailed explanation-4: -A substitution is a mutation that exchanges one base for another (i.e., a change in a single “chemical letter” such as switching an A to a G). Such a substitution could: change a codon to one that encodes a different amino acid and cause a small change in the protein produced.

Detailed explanation-5: -Missense Mutation. Missense mutations can also be benign and change an amino acid in a protein without altering its function.

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