OBJECTIVE LIFE SCIENCE
APPLIED BIOTECHNOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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deletion
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missense mutation
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nonsense mutation
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translocation
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Detailed explanation-1: -Base substitutions are the simplest type of gene-level mutation, and they involve the swapping of one nucleotide for another during DNA replication.
Detailed explanation-2: -Missense: A missense variant is a type of substitution in which the nucleotide change results in the replacement of one protein building block (amino acid) with another in the protein made from the gene. The amino acid change may alter the function of the protein.
Detailed explanation-3: -A nonsense mutation, or its synonym, a stop mutation, is a change in DNA that causes a protein to terminate or end its translation earlier than expected. This is a common form of mutation in humans and in other animals that causes a shortened or nonfunctional protein to be expressed.
Detailed explanation-4: -A substitution is a mutation that exchanges one base for another (i.e., a change in a single “chemical letter” such as switching an A to a G).