LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

BIOCHEMISTRY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A compound that distorts the active site, rendering the enzyme catalytically inactive is called
A
a uncompetitive inhibitor.
B
an allosteric effector.
C
an inactivator.
D
a competitive inhibitor.
E
none of the above
Explanation: 

Detailed explanation-1: -A compound that distorts the active site, rendering the enzyme catalytically inactive is called A UNCOMPETITIVE INHIBITOR.

Detailed explanation-2: -Competitive inhibition occurs when molecules very similar to the substrate molecules bind to the active site and prevent binding of the actual substrate. Penicillin, for example, is a competitive inhibitor that blocks the active site of an enzyme that many bacteria use to construct their cell…

Detailed explanation-3: -Competitive inhibitors work by camouflaging themselves as an enzyme’s natural substrate and binding to the enzyme’s active site, thereby blocking the natural substrate’s ability to bind to the enzyme’s active site. As binding affinity of a competitive inhibitor increases, enzyme activity decreases.

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