OBJECTIVE LIFE SCIENCE
BIOCHEMISTRY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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An enzyme is near maximum efficiency when
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its turnover number is near Vmax.
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kcat/KM is near 108 M-1s-1.
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k1 « k-1.
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kcat/KM is equal to kcat.
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KM is large when k2 exceeds k1.
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Explanation:
Detailed explanation-1: -In other words, a high kcat/Km ratio means the enzyme works well with not much substrate. This is called catalytic efficiency because if the enzyme is efficient, it means it doesn’t need much substrate to achieve a high reaction rate.
Detailed explanation-2: -One way to measure the catalytic efficiency of a given enzyme is to determine the kcat/km ratio. Recall that kcat is the turnover number and this describes how many substrate molecules are transformed into products per unit time by a single enzyme.
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