LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

BIOCHEMISTRY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Glycosphingolipids with several attached carbohydrates (including at least one sialic acid) are called:
A
plasmalogens
B
ceramides
C
sphingosides
D
gangliosides
E
cerebrosides
Explanation: 

Detailed explanation-1: -The term ganglioside defines a glycosphingolipid with one or more sialic acid residues (sulfated glycosphingolipids are also called gangliosides by some investigators). There is a well-known nomenclature system suggested by Svennerholm for the ganglio-series gangliosides (Figure 9.4).

Detailed explanation-2: -Gangliosides are sialic acid-containing glycosphingolipids. They occur especially on the cellular surfaces of neuronal cells, where they form a complex pattern, but are also found in many other cell types.

Detailed explanation-3: -Gangliosides: the most complex animal glycolipids. They contain negatively charged oligosacchrides with one or more sialic acid residues; more than 200 different gangliosides have been identified.

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