LIFE SCIENCE

Detailed explanation-1: -Holoenzyme is the result of a combination of Apoenzyme and Coenzyme. The Protein content of conjugated enzymes is referred to as Apoenzyme. The non-protein content of an enzyme is referred to as Coenzyme. Holoenzyme is a functional enzyme.

Detailed explanation-2: -Holoenzyme is a complete and catalytically active enzyme consisting of protein part (apoenzyme) together with its bound coenzyme and/or metal ions. A coenzyme or metal ion (non-protein part) that is very tightly or even covalently bound to the enzyme protein is called a prosthetic group.

Detailed explanation-3: -So the correct option is ‘Holoenzyme= Apoenzyme + Coenzyme’.

Detailed explanation-4: -On binding with the cofactor, it gets activated resulting in the formation of a holoenzyme that is functional. Thus the correct answer is option B.