OBJECTIVE LIFE SCIENCE
BIOCHEMISTRY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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to understand H-bonding between the complementary bases
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to understand how the bases are linked to ribose.
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to understand how bases are linked to deoxyribose.
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to understand the ability of nucleotides to act as energy carriers.
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to distinguish the 5’-end of a DNA strand from the 3’-end.
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Detailed explanation-1: -Nucleic acid bases can exist in multiple tautomeric forms due to the presence of solvent-exchangeable protons. Tautomers are structural isomers that differ from one another based on the position of proton(s) and double bonds (Antonov 2014).
Detailed explanation-2: -The spontaneous isomerization of a nitrogen base to an alternative hydrogen-bonding form, possibly resulting in a mutation. Reversible shifts of proton position in a molecule. bases in nucleic acids shift between keto and enol forms or between amino and imino forms.
Detailed explanation-3: -The reason for these mutations is the change of preferences between intermolecular hydrogen bonds resulting from the shift of the tautomeric equilibrium from the preferred amino form into the imino one.
Detailed explanation-4: -The two strands are held together by hydrogen bonds between pairs of bases: adenine pairs with thymine, and cytosine pairs with guanine.