LIFE SCIENCE

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OBJECTIVE LIFE SCIENCE

BIOCHEMISTRY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Proton transfer from an acid, lowering the free energy of a reaction’s transition state, is characteristic of
A
electrostatic catalysis.
B
nucleophilic catalysis.
C
general base catalysis.
D
general acid catalysis.
E
concerted acid-base catalysis.
Explanation: 

Detailed explanation-1: -Proton transfer from an acid, lowering the free energy of a reaction’s transition state, is characteristic of:-covalent catalysis.

Detailed explanation-2: -General acid-base catalysis is a type of catalysis that occurs when acidic or basic residue at the active site is useful in facilitating proton transfers in the reaction. Specific acid-base catalysis is a process in which the reaction rate depends on the specific base and not on the other bases in the solution.

Detailed explanation-3: -Acid-Base Catalysis is involved in any reaction mechanism that requires the transfer of a proton from one molecule to another. It is very common to see this mechanism combined with Covalent Catalysis as many nucleophiles are activated by the removal of a proton, including alcohol, thiol, and amine functional groups.

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