LIFE SCIENCE

Detailed explanation-1: -The part of the enzyme where the substrate binds is called the active site (since that’s where the catalytic “action” happens). A substrate enters the active site of the enzyme. This forms the enzyme-substrate complex.

Detailed explanation-2: -The substrate binds to the enzyme by interacting with amino acids in the binding site. The binding site on enzymes is often referred to as the active site because it contains amino acids that both bind the substrate and aid in its conversion to product.

Detailed explanation-3: -The simplest model of enzyme-substrate interaction is the lock-and-key model, in which the substrate fits precisely into the active site (Figure 2.24). In many cases, however, the configurations of both the enzyme and substrate are modified by substrate binding-a process called induced fit.

Detailed explanation-4: -Key Points. An active site is a specific location found in the enzyme where a substrate binds to catalyze the reaction. It is also called “Enzyme catalytic surface”. About 10-15 amino acid residues combine to form an active site.