OBJECTIVE LIFE SCIENCE
BIOCHEMISTRY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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non-oxidative phase
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oxygen phase
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oxidative phase
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non-oxygen phase
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Detailed explanation-1: -Definition: A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP.
Detailed explanation-2: -Nicotinamide adenine dinucleotide (NAD+) is a molecule formed from vitamin B3 and ATP that acts as a carrier molecule for electrons and hydrogen. NAD+ becomes NADH when two electrons and a hydrogen are added to the molecule. One molecule of glucose can form 10 molecules NADH.
Detailed explanation-3: -NAD+ reduction to NADH is featured in glycolysis, pyruvate dehydrogenase, and the tricarboxylic acid cycle (TCA cycle).
Detailed explanation-4: -In this shuttle, NADH is oxidized to NAD+ in the cytosol and NAD+ is reduced to NADH in mitochondria. NAD+ is used as an electron acceptor during glycolysis, whereas NADH is used by mitochondrial complex I to drive the mitochondrial electron transport chain (ETC).