LIFE SCIENCE

Detailed explanation-1: -Temperature: Raising temperature generally speeds up a reaction, and lowering temperature slows down a reaction. However, extreme high temperatures can cause an enzyme to lose its shape (denature) and stop working. pH: Each enzyme has an optimum pH range. Changing the pH outside of this range will slow enzyme activity.

Detailed explanation-2: -What three things can denature enzymes? Enzymes can be denatured in three different ways: increase beyond the optimal temperature of an organism; decreases in pH, resulting in acidity; and increases in pH, producing a basic environment. These factors disrupt the bonds holding an enzyme together.

Detailed explanation-3: -Higher temperatures disrupt the shape of the active site, which will reduce its activity, or prevent it from working. The enzyme will have been denatured . Enzymes therefore work best at a particular temperature.

Detailed explanation-4: -Several factors affect the rate at which enzymatic reactions proceed-temperature, pH, enzyme concentration, substrate concentration, and the presence of any inhibitors or activators.