OBJECTIVE LIFE SCIENCE
BIOTECHNOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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ricer
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dicer
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RISC
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slicer
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Detailed explanation-1: -Dicer is a multi-domain RNase III-related endonuclease responsible for processing double-stranded RNA (dsRNA) to small interfering RNAs (siRNAs) during a process of RNA interference (RNAi). It also catalyses excision of the regulatory microRNAs from their precursors.
Detailed explanation-2: -The RNAi pathway is initiated by the enzyme dicer (see below), which cleaves long, double-stranded RNA (dsRNA) molecules into short fragments of 20–25 base pairs.
Detailed explanation-3: -Invertebrates rely on Dicer to cleave viral double-stranded RNA (dsRNA), and Drosophila Dicer-2 distinguishes dsRNA substrates by their termini. Blunt termini promote processive cleavage, while 3′ overhanging termini are cleaved distributively.