LIFE SCIENCE

Detailed explanation-1: -In conjunction with his studies of the tumor virus SV40, in 1972, Paul Berg succeeded in inserting DNA from a bacterium into the virus’ DNA. Berg thereby created the first DNA molecule made of parts from different organisms. This type of molecule became known as hybrid DNA or recombinant DNA.

Detailed explanation-2: -American biochemist Paul Berg made outstanding contributions to biochemistry and molecular biology for over fifty years. As a young researcher he resolved several key problems in metabolic chemistry, and went on to discover the mechanisms by which DNA and RNA direct the synthesis of proteins in living systems.

Detailed explanation-3: -The Nobel laureate Paul Berg initiated genetic manipulation and pioneered genetic engineering. He was also one of the initiators of setting up guidelines for carrying out recombinant DNA experiments. He was an innovative scientist and cared for the impact of science on society.

Detailed explanation-4: -Cohen and H. Boyer constructed the first recombinant DNA using antibiotic resistance genes present on the plasmid of drug resistance strains of E. coli. This gene was linked to the native plasmid of Salmonella typhimurium.