LIFE SCIENCE

Detailed explanation-1: -DNA is wrapped around core histones, forming a nucleosome fiber (10-nm fiber). This fiber has long been assumed to fold into a 30-nm chromatin fiber and subsequently into helically folded larger fibers or radial loops.

Detailed explanation-2: -A zig-zag array of the nucleosomes, in which DNA is wrapped around spaced core histone octamers, is referred to throughout as the 10-nm chromatin fiber (Figure 1, bottom center) [1, 2]. An interphase chromosome at its core is a single very long 10-nm chromatin fiber that is highly organized in the nucleus.

Detailed explanation-3: -Each nuclesome is composed of DNA wound 1.65 times around eight histone proteins. Nucleosomes fold up to form a 30-nanometer chromatin fiber, which forms loops averaging 300 nanometers in length.

Detailed explanation-4: -Each of these tiny beads is a called a nucleosome and has a diameter of approximately 11 nm. The nucleosome is the fundamental subunit of chromatin. Each nucleosome is composed of a little less than two turns of DNA wrapped around a set of eight proteins called histones, which are known as a histone octamer.