OBJECTIVE LIFE SCIENCE
CELL BIOLOGY
Question
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Ligands are signaling molecules that bind to receptors. Which of the following statements is true of ligands?
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All ligands are proteins.
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Each ligand is only able to bind to one specific receptor
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Ligands can bind to cell-surface receptors, but they cannot enter the cell
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Ligands bond to receptor proteins and cause the protein to relay a message to intracellular proteins.
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Explanation:
Detailed explanation-1: -Ligands that can enter the cell Small, hydrophobic ligands can pass through the plasma membrane and bind to intracellular receptors in the nucleus or cytoplasm.
Detailed explanation-2: -When a ligand binds to a protein, it undergoes a conformational change which in turn leads to a physiological response. The time a ligand spends attached to a receptor or specific protein is a function of the affinity between the ligand and the protein.
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