OBJECTIVE LIFE SCIENCE
CELL BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Mitosis
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Meiosis
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Crossing over
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Active transport
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Detailed explanation-1: -Colchicines prevent spindle formation during mitotic metaphase. Thus, it prevents the separation of chromosomes during anaphase stage. Hence, the correct answer is option B.
Detailed explanation-2: -Answer and Explanation: Colchicine is a drug that interferes with mitotic cell division during the cell cycle. Colchicine hinders the production of spindle fibers, and hence metaphase does not progress, and the cell cycle stops at this stage.
Detailed explanation-3: -At a cellular level, colchicine is an antimitotic agent that inhibits mitosis by preventing the polymerization of tubulin, 11, 12 a constituent microtubule protein, thereby disturbing those processes dependent on microtubule function such as cell motility, intracellular movement, cell polarity, and mitosis.
Detailed explanation-4: -DESCRIPTION: Colchicine is a highly toxic plant hormone that is used medically in the treatment of gout and in scientific research. Colchicine stops the process of cell division (it is an antimitotic agent). Exposure to colchicine can be fatal in very small doses (e.g., 7 to 65 mg).