LIFE SCIENCE

Detailed explanation-1: -The rough endoplasmic reticulum (RER) is so named for the appearance of its outer surface, which is studded with protein-synthesizing particles known as ribosomes.

Detailed explanation-2: -The RER is termed “rough” due ribosomal attachments to the surface compared to the SER, which does not have ribosomes.

Detailed explanation-3: -Ribosomes on the rough endoplasmic reticulum are called ‘membrane bound’ and are responsible for the assembly of many proteins.

Detailed explanation-4: -Ribosomes are found ‘free’ in the cytoplasm or bound to the endoplasmic reticulum (ER) to form rough ER. In a mammalian cell there can be as many as 10 million ribosomes. Several ribosomes can be attached to the same mRNA strand, this structure is called a polysome.

Detailed explanation-5: -RER is arranged in aggregates of flat cisternae that may be found throughout the cytoplasm. It is more frequently distributed in the perinuclear, pericanalicular, and vascular regions of hepatocytes, and it is more abundant in periportal cells than in centrilobular cells.