LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

CELL BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the most likely pathway taken by a newly synthesized protein that will be secreted by a cell?
A
ER, golgi, nucleus
B
Golgi, ER, lysosome
C
nucleus, ER, Golgi
D
ER, golgi, vesicles that fuse with plasma membrane
Explanation: 

Detailed explanation-1: -These experiments defined a pathway taken by secreted proteins, the secretory pathway: rough ER → Golgi → secretory vesicles → cell exterior.

Detailed explanation-2: -As discussed in Chapter 12, newly synthesized proteins enter the biosynthetic-secretory pathway in the ER by crossing the ER membrane from the cytosol.

Detailed explanation-3: -Newly synthesized proteins enter the endomembrane system through the endoplasmic reticulum. From there them move through the Golgi apparatus and into either the Secretory Pathway or the Lysosomal Pathway.

Detailed explanation-4: -The newly synthesized proteins reach the Golgi apparatus, where they are modified, processed, sorted and dispatched towards their final destination.

Detailed explanation-5: -The secretory pathway refers to the endoplasmic reticulum, Golgi apparatus and the vesicles that travel in between them as well as the cell membrane and lysosomes. It’s named ‘secretory’ for being the pathway by which the cell secretes proteins into the extracellular environment.

There is 1 question to complete.