OBJECTIVE LIFE SCIENCE
CELL BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which portion of ATP synthase is hydrophilic
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F1
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F0
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Either A or B
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None of the above
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Explanation:
Detailed explanation-1: -The F1 portion of ATP synthase is hydrophilic and responsible for hydrolyzing ATP. The F1 unit protrudes into the mitochondrial matrix space. Subunits and make a hexamer with 6 binding sites. Three of them are catalytically inactive and they bind ADP.
Detailed explanation-2: -Solvated F1 is able to hydrolyze ATP and experiments pioneered by Noji et al. (Nature 386:299-302, 1997) have shown that ATP hydrolysis in F1 drives rotation of the central stalk.
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