LIFE SCIENCE

Detailed explanation-1: -Enzymes are protein molecules that get denatured at high temperatures. High heat breaks hydrogen and ionic bonds leading to disruption in enzyme shape. The enzyme loses its activity and can no longer bind to the substrate.

Detailed explanation-2: -Higher temperature generally causes more collisions among the molecules and therefore increases the rate of a reaction. More collisions increase the likelihood that substrate will collide with the active site of the enzyme, thus increasing the rate of an enzyme-catalyzed reaction.

Detailed explanation-3: -If the enzyme changes shape, the active site may no longer bind to the appropriate substrate and the rate of reaction will decrease. Dramatic changes to the temperature and pH will eventually cause enzymes to denature.