LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

DEVELOPMENTAL BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Maternal/Cytoplasmic determinants start the earliest differentiation. How do cells in the later embryo decide how to further differentiate?
A
position-for example, ectoderm cells will not differentiate to become muscle cells because they are located on the outside of the developing embryo.
B
cell to cell communication-cells communicate with one another to determine their position and which steps are needed to further differentiate. For example, a cell in the position of the pancreatic bud will be at the interface between endoderm and mesoderm approximately in the middle of the embryo, The cell will determine its position by communicating with the cells around itself.
C
cell to cell induction-special groups of cells will produce gene products that direct the further differentiation of the surrounding cells. A great example is the ZPA which directs limb development with the sonic hedgehog protein.
D
None of the above
Explanation: 

Detailed explanation-1: -For our purposes, cytoplasmic determinants are defined as entities localized in specific cytoplasmic regions of the egg or embryonic cell that bias the cells containing them to assume particular properties or fates during embryogenesis.

Detailed explanation-2: -They play a major role in the development of the embryo’s organs. Each type of cell is determined by a particular determinant or group of determinants. Thus, all the organs of the future embryo are distributed and operating well thanks to the right position of the cytoplasmic determinants.

Detailed explanation-3: -Cytoplasmic determinants are maternal substances in the egg that affect the course of early development. The integration of cytoplasmic determinants in a cell influences its developmental fate by regulation of gene expression all through cell differentiation.

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