OBJECTIVE LIFE SCIENCE
GENETICS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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It is most likely to occur in females because they have two X chromosomes.
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It is most likely to occur in males because they only have one X chromosome.
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It will never occur in males because they have a Y chromosome to protect them.
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It will occur in females if they have at least one chromosome with the disorder.
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Detailed explanation-1: -So, the correct answer is ‘Recessive trait carried by X-chromosome’.
Detailed explanation-2: -Hemophilia A and hemophilia B are inherited in an X-linked recessive pattern . The genes associated with these conditions are located on the X chromosome, which is one of the two sex chromosomes . In males (who have only one X chromosome), one altered copy of the gene in each cell is sufficient to cause the condition.
Detailed explanation-3: -Hemophilia is an X-linked recessive hereditary disorder that classically affects males due to the presence of only one X chromosome in males. Females are usually carriers due to the presence of counterpart X chromosome, but many times manifestations of hemophilia are seen in heterozygous carrier females.
Detailed explanation-4: -Since males have only a single copy of any gene located on the X chromosome, they cannot offset damage to that gene with an additional copy as can females. Consequently, X-linked disorders such as Hemophilia A are far more common in males.