LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

GENETICS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Hemophilia is a recessive sex-linked trait which affects the ability of blood to clot. What is the probability of a carrier matter and unaffected father having a son with hemophilia?
A
25%
B
100%
C
75%
D
50%
Explanation: 

Detailed explanation-1: -If the son gets his mother’s X chromosome with the hemophilia gene he will have hemophilia. If he inherits his mother’s other X chromosome, he will have normal blood clotting. So a carrier’s son has a 50% chance of having hemophilia.

Detailed explanation-2: -Hemophilia is an X-linked recessive hereditary disorder that classically affects males due to the presence of only one X chromosome in males. Females are usually carriers due to the presence of counterpart X chromosome, but many times manifestations of hemophilia are seen in heterozygous carrier females.

Detailed explanation-3: -Hemophilia is & sex-linked recessive trait in humans If a father and & son are both hemophiliacs; but the mother Is normal; her genotype must be: 0 Xhy XhXh 0 XhXh XHXH.

Detailed explanation-4: -Hemophilia is caused by the lack of clotting factor VIII or IX in the blood. In most cases, hemophilia is passed down through families (inherited). Most of the time, it is passed to male children.

There is 1 question to complete.