OBJECTIVE LIFE SCIENCE
GENETICS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Phenylketonuria (PKU) is inherited as a recessive condition. A man with PKU marries a woman without any alleles for PKU. What is the probability that their child will inherit PKU?
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0%
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25%
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50%
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75%
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Explanation:
Detailed explanation-1: -Autosomal recessive inheritance pattern You get one from each parent. Their health is rarely affected because they have only one changed gene. Two carriers have a 25% chance of having an unaffected child with two unaffected genes. They have a 50% chance of having an unaffected child who also is a carrier.
Detailed explanation-2: -Classical PKU is an autosomal recessive disorder, caused by mutations in both alleles of the gene for phenylalanine hydroxylase (PAH), found on chromosome 12. In the body, phenylalanine hydroxylase converts the amino acid phenylalanine to tyrosine, another amino acid.
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