OBJECTIVE LIFE SCIENCE
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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ATTTGAGCC-OriginalATTGAGCC-MutatedThe example above is an example of a
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Insertion-Frameshift
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Deletion-Substitution
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Deletion-Frameshift
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All of the above
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Explanation:
Detailed explanation-1: -Two frameshift mutations in the CFTR genes cause cystic fibrosis (one involves the insertion of two nucleotides, and the other involves the deletion of one nucleotide).
Detailed explanation-2: -It is a type of frameshift mutation characterized by the loss of one or more nucleotides from the segment of DNA. Example of deletion mutation is DiGeorge syndrome. DiGeorge syndrome is a disorder caused due to the deletion of a small segment of chromosome 22.
Detailed explanation-3: -An insertion or deletion involving a number of base pairs that is not a multiple of three, which consequently disrupts the triplet reading frame of a DNA sequence.
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