LIFE SCIENCE

Detailed explanation-1: -The D-loop occurs in the main non-coding area of the mitochondrial DNA molecule, a segment called the control region or D-loop region. Replication of the mitochondrial DNA can occur in two different ways, both starting in the D-loop region.

Detailed explanation-2: -Mitochondrial DNA replication is initiated at the origin for H-strand DNA replication (OH) and the origin for L-strand DNA replication (OL). During the initiation phase, replication is limited to the H strand only; no simultaneous L-strand synthesis occurs.

Detailed explanation-3: -The control region and mtDNA D-loop are sometimes used synonymously in the literature; specifically the control region includes the D-loop along with adjacent transcription promoter regions. For this reason, the control region is also known by the acronym DLP, standing for D-Loop and associated Promoters.