LIFE SCIENCE

Detailed explanation-1: -The Structural Classification of Proteins (SCOP) database is a largely manual classification of protein structural domains based on similarities of their structures and amino acid sequences. A motivation for this classification is to determine the evolutionary relationship between proteins.

Detailed explanation-2: -SCOPe (Structural Classification of Proteins-extended) is a database developed at the Berkeley Lab and UC Berkeley to extend the development and maintenance of SCOP. SCOP was conceived at the MRC Laboratory of Molecular Biology, and developed in collaboration with researchers in Berkeley.

Detailed explanation-3: -The SCOP database, created by manual inspection and abetted by a battery of automated methods, aims to provide a detailed and comprehensive description of the structural and evolutionary relationships between all proteins whose structure is known.