LIFE SCIENCE

Detailed explanation-1: -There are four main enzymes that facilitate DNA replication: helicase, primase, DNA polymerase, and ligase.

Detailed explanation-2: -Similarities Between DNA Ligase and DNA Polymerase DNA ligase and DNA polymerase are two enzymes whose substrate is double-stranded DNA. They catalyze the formation of phosphodiester bonds. Both enzymes play an important role in DNA replication and repair.

Detailed explanation-3: -DNA ligase is responsible for joining DNA fragments by catalyzing the formation of phosphodiester bonds between nucleotides. DNA polymerase is responsible for synthesis of DNA from its building blocks (nucleotides) using template DNA. This is the key difference between DNA ligase and DNA polymerase.