LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

MOLECULAR BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Further processing of eukaryotic mRNA includes
A
Splicing and tailing
B
Caping and tailing
C
caping, tailing and splicing
D
Splicing only
Explanation: 

Detailed explanation-1: -There is an addition of 7-methylguanylate at the 5’ end of the mRNA. This process is known as the capping of the mRNA. At the 3’ end of the mRNA, there is an addition of a chain of adenine nucleotides. This is known as the poly-A tail or the tailing mechanism.

Detailed explanation-2: -A 5′ cap is added to the end of pre-mRNA while elongation is still in progress. The 5′ cap protects the mRNA from degradation and assists in ribosome binding during translation. A roughly 200 nucleotide-long poly-A tail is also added to the 3′ end of the pre-mRNA once elongation is complete.

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