LIFE SCIENCE

Detailed explanation-1: -Locus is a term that we use to tell us where on a chromosome a specific gene is. So it’s really the physical location of a gene on a chromosome.

Detailed explanation-2: -In genetics, a locus (plural loci) is a specific, fixed position on a chromosome where a particular gene or genetic marker is located.

Detailed explanation-3: -A specific position along a chromosome is called a locus. Each gene occupies a specific locus (so the terms locus and gene are often used interchangeably). Each locus will have an allelic form (allele). The complete set of alleles (at all loci of interest) in an individual is its genotype.

Detailed explanation-4: -The definition of a Locus-Specific Database (LSDB) is “a collection of sequence variants in a specific gene that causes a Mendelian disorder or change in phenotype” [Cotton et al, 2008].