OBJECTIVE LIFE SCIENCE
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Identify the SUBSTITUTION mutation from the following DNA sequence:ATG CCA AAT
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ATG TCA AAT
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ATG CCT AAA T
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ATC CA AT
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ATG CCA AAT
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Explanation:
Detailed explanation-1: -Base substitution Base substitutions are the simplest type of gene-level mutation, and they involve the swapping of one nucleotide for another during DNA replication. For example, during replication, a thymine nucleotide might be inserted in place of a guanine nucleotide.
Detailed explanation-2: -The blood disease Sickle-cell anemia is caused by a simple substitution mutation. In the mutation, a single nucleotide is replaced in the portion of DNA which codes for a unit of hemoglobin. Hemoglobin is a multi-protein complex, responsible for carrying oxygen and supporting the shape of blood cells.
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