OBJECTIVE LIFE SCIENCE
MOLECULAR BIOLOGY
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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If below is the wild-type DNA sequence, which one shows a point mutation?5’-ATTCGC-3’
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5’-AATTCGC-3’
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5’-ATCCGC-3’
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5’-ATCGC-3’
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5’-ATTCGC-3’
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Explanation:
Detailed explanation-1: -A missense mutation results in a different amino acid being incorporated into the resulting polypeptide. The effect of a missense mutation depends on how chemically different the new amino acid is from the wild-type amino acid. The location of the changed amino acid within the protein also is important.
Detailed explanation-2: -Types of Point Mutations We are going to focus on the following point mutations: frameshift, silent, nonsense, and missense. Let’s start with a frameshift mutation, where there’s an insertion or deletion of one or more bases.
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