OBJECTIVE LIFE SCIENCE
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Splicosome
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Rho independent
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RNA polymerase
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Rho dependent
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Detailed explanation-1: -Once transcribed into pre-mRNA, these introns must be removed within the spliceosome before export of the processed mRNA to the cytoplasm, where it is translated into protein. Although intron loss has been demonstrated experimentally, several mysteries remain regarding the origin and propagation of introns.
Detailed explanation-2: -The extensive interplay of RNA and proteins in aligning the pre-mRNA’s reactive groups, and the presence of both RNA and protein at the core of the splicing machinery, suggest that the spliceosome is an RNP enzyme.
Detailed explanation-3: -Biology of Adult Myelocytic Leukemia and Myelodysplasia Spliceosomes are complexes composed of small nuclear RNA (snRNA) that remove introns in protein-encoding genes.