OBJECTIVE LIFE SCIENCE
MOLECULAR BIOLOGY
Question
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Origin of replication in bacteria usually contains
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GC rich sequence
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Both AT and GC rich sequence
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No particular stretch of sequence
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AT rich sequence
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Explanation:
Detailed explanation-1: -The AT-rich regions in bacterial chromosomal origins of replication are usually located on one side of a cluster of DnaA-box sequences. In case of the plasmid origins, this rule applies to the AT-rich region and the iteron sequences recognized by initiator proteins.
Detailed explanation-2: -Bacterial replication origins carry DNA sequence motifs recognized by DnaA and other proteins, and an AT-rich region named the DNA unwinding element (DUE). Among bacteria however, the presence, relative arrangement, and position of these DNA motifs are not conserved.
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