LIFE SCIENCE

Detailed explanation-1: -In 1978, the Nobel Prize in Physiology or Medicine was awarded jointly to Werner Arber, who predicted the existence of restriction enzymes, Hamilton Smith, who discovered the first Type II restriction enzyme, and Nathans, who demonstrated how to use the restriction enzymes to analyze viral DNA.

Detailed explanation-2: -Wilcox, Smith isolated and characterized the first Type II restriction endonuclease (HindII) from Haemophilus influenzae and determined the sequence of its cleavage site (2, 3). In recognition of this discovery, he was awarded the 1978 Nobel Prize in Physiology or Medicine with Werner Arber and Daniel Nathans.

Detailed explanation-3: -Restriction enzymes were discovered and characterized in the late 1960s and early 1970s by molecular biologists Werner Arber, Hamilton O.